Free BookMucosal Delivery of Biopharmaceuticals Biology Challenges and Strategies

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Published on: 2014-02-03
Released on: 2014-02-03
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Biopharmaceutical medicines, the newest class of therapeutics, are quite heterogeneous and include a range of molecules such as proteins, peptides, vaccines and nucleic acids, with use in virtually all therapeutic fields (e.g. cancer and infectious diseases, vaccination, metabolic dysfunctions) and diagnostics. This edited book gives a concise and up-to-date overview of the biological features justifying the use of different human mucosa as delivery routes for biopharmaceuticals, the technological strategies that have been followed so far regarding the optimization of mucosal potentialities as well as the challenges that arise with the advent of new biopharmaceutical drugs and alternative means of administration. Following a brief introduction, the first section addresses general aspects of the biology of mucosal tissues and their unique aspects toward beneficial or deleterious interaction with biopharmaceuticals and their delivery systems. The second part reviews the different delivery strategies that have recently been investigated for different mucosal sites. The third section describes the development and clinical applications of drug delivery systems and products enclosing biopharmaceuticals for mucosal delivery, with a focus on the most successful case studies of recent years. The last section briefly centers on relevant aspects of the regulatory, toxicological and market issues of mucosal delivery of biopharmaceuticals.​ Scientists and researchers in the fields of drug delivery, material science, biomedical science and bioengineering as well as professionals, regulators and policy makers in the pharmaceutical, biotechnology and healthcare industries will find in this book an important compendium of fundamental concepts and practical tools for their daily research and activities. Conferences and Meetings on Molecular Biology Conferences and Meetings on Molecular Biology. Conference-Service.com offers as part of our business activities a directory of upcoming scientific and technical ... Influence of Immunogenicity on the Long-Term Efficacy of ... Original Article. Influence of Immunogenicity on the Long-Term Efficacy of Infliximab in Crohn's Disease. Filip Baert M.D. Maja Noman M.D. Severine Vermeire M.D ... DNA vaccination - Wikipedia DNA vaccination is a technique for protecting against disease by injection with genetically engineered DNA so cells directly produce an antigen producing a ... Linhardt Labs - Papers 224. "Analysis of fluorescently labeled oligosaccharides by capillary electrophoresis and electrospray ionization mass spectrometry. "H. G. Bazin M.W. Wolff R.J ... Lebrikizumab Treatment in Adults with Asthma NEJM Original Article. Lebrikizumab Treatment in Adults with Asthma. Jonathan Corren M.D. Robert F. Lemanske Jr. M.D. Nicola A. Hanania M.D. Phillip E. Korenblat M ... Course Schedule Advanced Academic Programs Johns ... $4074. Michael Lebowitz. Thursday 6:00 - 9:20; 1/12 - 4/27. This course is a continuation of 410.603 (Advanced Cell Biology I) and further explores cell organization ... Books@Ovid 100 Cases for Medical Data Interpretation; 100 Cases in Acute Medicine; 100 Cases in Dermatology; 100 Cases in General Practice; 100 Cases in Orthopaedics and ... Research projects - Australian Institute for ... Project keywords. Nanobiotechnology Health Antibody Targeted delivery Nanoparticle Cancer Cytotoxins. Project summary. The research projects are associated with ... ARCHIVED - Book of Abstracts - Minister of Health Table of Contents for 2007 Health Canada Book of Abstracts Course Descriptions Advanced Academic Programs Johns ... This course is a continuation of 410.603 (Advanced Cell Biology I) and further explores cell organization and subcellular structure. Students examine cell-to-cell ...
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